Seminar – Using DoE In Combination With Parallel Reactor Platforms

DATE & TIME: Friday April 28th 2017 // 12.30 pm to 5.30 pm
VENUE: Hotel Aditya Park | Aditya Trade Centre | Ameerpet | Hyderabad -38
Tel: +91-040- 66788888  // Mobile:7032900753 // Fax : +91 40 66789999
www.hoteladityapark.com

SYNOPSIS
The increase in competitive pressures from within the chemical process industry requires that more processes be developed quickly, efficiently and with better performance.
The use of multiple (parallel) reactor platforms is becoming an established practice in the pharmaceutical industry, including the fulfilment of QbD regulation as laid out by the US Food and Drug Administration and more generally the specific use of DoE to direct experimental efforts and analyze data.
This seminar will present key results from many different process development studies to illustrate the range of
parallel reaction instruments available. Examples will include those from organic and synthetic chemistry, as well as heterogeneous catalysis (including hydrogenation in flow reactors) and crystallization studies will be used to describe the benefits of these techniques

Presenter: Dr. Jasbir Singh, CEO, HEL Ltd

This is a FREE SEMINAR and places are limited. Please register NOW to book your attendance by clicking or copying link:
http://helgroup.com/marketing/doeindia/

EXCLUSIVE EVENT – Batteries and Fuel Cell Seminar- March 30-31st, 2016

The seminar program focuses on present and future needs of portable and stationary electrochemical energy sources and highlights the latest technological developments designed to satisfy application requirements.The program reviews primary, rechargeable, reserve batteries, fuel cells, ultra-capacitors systems and their accessories.
The seminar program reviews typical cycle life aspects of designing and manufacturing energy source solutions: from application energy requirements, power source electrical and mechanical design, cells selection, cells evaluation tests, battery prototype, acceptance tests, design and manufacturing techniques, testing, mass production, safety issues, transportation, use and disposal.

Special focus is given to battery design and testing aspects which are vital tools for battery solution.
The program trains attendees on safety issues along the energy source solution cycle life.

The program focuses on electric vehicle and Batteries, Super Capacitors, Fuel Cells and Metal Air systems for EV`s.

Key Benefits
Batteries & Fuel Cells Seminar provides:

  • Full review of current and future electrochemical energy sources.
  • Training on cells selection, design, manufacturing, testing, safety, and transportation and disposal aspects of energy sources.
  • Basic knowledge for new industry members entering the field.
  • Expands the knowledge of industry members already working in the field.
  • Training on Energy Sources Database software – a vital tool for optimal energy source design.
Seminar Program
Topics

– Battery characteristics
– Primary cells & batteries
– Rechargeable cells & batteries
– Lithium rechargeable cell
– Manufacturing process
– Battery chargers
– Military batteries
– Thermal & reserve batteries
– Battery design process
– Battery safety
– Battery disposal
– The “smart battery”
– Battery testing systems
– Energy storage for the grid
– Fuel cells
– Ultra Capacitors
-The E-Mobility revolution
– xEV`s Batteries
– xEV`s Fuel Cells and Metal Air
systems
– xEV`s battery swap
– xEV`s Charging infrastructure

Who Should Attend?

  • Battery and energy sources users
  • Pack assemblers
  • Cell makers
  • Energy sources suppliers
  • Academic researchers
  • R&D engineers
  • Market researchers
  • Safety supervisors
  • Battery shippers and disposals
  • E-Mobility industry members
  • Others industry members

BOOK NOW BY CLICKING ON:
http://helgroup.com/marketing/batteries-and-fuel-cell-seminar-march-30-31st-2016

 

In-conjunction with:

“NEW” Tandem Gas Analyser Data Capture Software

The new Tandem gas analyser data capture software allows the convenient monitoring and visualisation of exhaust gas data from all Tandem Gas Analysers
The Magellan BioTech, Tandem, data capture software for all Tandem gas analysers

 

Advantages of the Tandem data capture software:

| Real-time monitoring of %CO2 and %O2 from the off-gas of any bioreactor
| Export data in CSV format
| Available as a stand-alone portable unit
| Works with any Tandem gas analyser
| Run up to 18 parallel processes
| Simple to use
| Automatically calculates CER, OUR & RQ with HEL BioXplorer systems

The Tandem Family of Gas Analysers offers you sophisticated CO2 and O2 gas measurement at a similar price to your other standard probes and sensors. Formerly the reserve of expensive equipment, you can now afford dedicated, individual, on-line monitoring and control of your processes. You gain the reliability and the flexibility required in your facility. The Tandem Gas Analysers provide portable systems with option of standalone software.

The Tandem gas analysers off the following benefits:

Greater understanding of your cells and processes
| Physiological state measurement on-line
| Scale-up and scale-down predictions
| Batch variation studies: feature analysis
| Metabolic flux analysis and mass-balance calculations

Increase the reliability and repeatability of your processes
| Accurate fed-batch control
| Metabolic activity based feeding
| Repeatable event decisions: induction, infection, harvesting etc.
| Dedicated, continuous, standard signals for all your reactors
| Automatic calculation of RQ, CER, OUR, and RQ
| Integrates to any reactor size (250 ml – 100 m3)

Fast Optimisation & Safe Scale-up – Simular Reaction Calorimeter

 Fast Optimisation & Safe Scale-up – Simular Reaction Calorimeter

Essential tool for process development chemists
HEL’s reaction calorimetry system provides a unique blend of features that are considered indispensable for process development:
|  Automation accelerates development, freeing up chemist time
|  Repeatable runs independent of operator
|  Ease of use including automatic on-line heat release rate results
|  Directly enables prediction of cooling duty, thermal hazard and possible methods for risk reduction

The Simular is based around reaction vessels that are easy to use but also match the geometry and performance of large-scale vessels. Designs are available to suit a range of pressures and temperatures.

Fast Optimisation & Safe Scale-up – Simular Reaction Calorimeter

 

HEL CAT 7 Design Improvements

Change In Design For CAT 7

Cold fingers have been removed (unscrewed) and silicone seals no longer used. Instead, special PTFE plugs are placed in each vial.
This is the only change.

add ptfe and top cover for new design of the HEL CAT 7

Why Change?- The Benefits

Solvent loss from vials during an experiment is much reduced and reproducibility is improved. Also, chemical compatibility is improved by removal of silicone seals and use of only PTFE.
The operation remains simple.

Older CAT 7 Units

Existing CAT7 units can be updated easily. Cold fingers must be unscrewed by the user (easily done by hand) and a set of PTFE plugs purchased.

Older CAT 7 Units Existing CAT7 units can be updated easily. Cold fingers must be unscrewed by user (easily done by hand) and a set of PTFE plugs purchased.

 

 

New HEL BioXplorer 100 & 400 Mini-Bioreactor System

The Mini-Bioreactor System For Rapid Parallel Bioprocessing

Introducing The BioXplorer 100 & BioXplorer 400 Mini-Bioreactor System

The feature rich, modular design with an extensive list of options means the BioXplorer 100 and 400 can be adapted to any application including microbial fermentation, C1 Gas fermentation and mammalian cell culture. These mini-bioreactors provide the ideal platform for bioprocess development and optimisation using 4 or 8 reactors in parallel with fermentation working volumes from 20 ml to 400 ml (depending on c.onfiguration)

The BioXplorer 100

The Mini-Bioreactor System For Rapid Parallel BioprocessingThe BioXplorer 100 is a high throughput, bioprocess screening system
designed for fermentation working volumes of just 20ml to 150ml in blocks of 8 individually controlled bioreactors.
Blocks can be combined to give even larger number of parallel reactors.
The BioXplorer 100 boosts productivity and enables rapid screening, process development and full DoE experiments to be performed efficiently.
| Fully automated, high information content screening tool ideal for DOE studies
| Most compact system for optimised use of bench space
| Highly cost effective system for scalable, rapid, high throughput bioprocessing
| Ideal for cell line/strain screening, media optimisation and small scale process development
| Suitable for robotic integration
| Choice of reactor sizes and types including elevated pressure design (5 bar or 10 bar options)

download pdf

The BioXplorer 400

Obtain a greater understanding of all process parameters at working volumes from 50 ml to 400 ml

The BioXplorer 400 provides the ideal platform for bioprocess development and optimisation using 4 or 8 reactors in parallel with fermentation working volumes from 50ml to 400ml.
This volume range provides high-quality data for reliable prediction of large scale performance over a wide range of conditions.
The system is highly flexible allows interchangeable use of smaller vessels with working volumes of just 20ml. The smaller vessels are highly suitable for data rich screening campaigns.
| Most versatile bioprocessing platform for bioprocess development and optimisation
| High information content and excellent scalability to large-scale bioreactors
| Reduce media costs and optimise the use of bench space
| Optional elevated pressure design to 10 bar

download pdf

 

Specifications

specifications for the BioXplorer 100 and 400, with working volumes, options

 

Rapidly Evaluate Catalysts & Optimize Reaction Conditions

With the HEL CAT 7, CAT 18, CAT 24, PluCAT, DigiCAT products for Rapidly Evaluate Catalysts & Optimize Reaction Conditions

One challenge faced by researchers in catalyst development is the need to quickly evaluate different catalysts and optimise reaction conditions. However, accessing affordable, high pressure, high temperature screening devices is equally challenging. The HEL CAT blocks:
|Provide an affordable, entry level range of catalyst research tools.
|Are available in 7, 18 or 24 vial configurations the CAT blocks allow primary catalyst screening and basic process
optimisation at relatively low cost.
|Can be used with conventional hotplate stirrers and all gas and pressure fittings are preinstalled.
|Are widely used successfully at many Universities both as research and teaching tools.
|Allows to undertake rapid parallel catalysis and thereby facilitate quicker downstream analysis.
With the HEL CAT 7, CAT 18, CAT 24, PluCAT, DigiCAT products for Rapidly Evaluate Catalysts & Optimize Reaction Conditions

 

 

What Are The KPI’s For Thermal Control Data Based On ISOTHERMAL Calorimetry?

We have prepared a FREE application note, which highlights key performance indicators of thermal control data based on isothermal calorimetry, which can be found here or copy and paste the link below in your browser http://helgroup.com/marketing/isothermalDOWNLOAD OUR FREE APPLICATION NOTE HIGHLIGHTING KPI’S FOR THERMAL CONTROL
DATA BASED
ON ISOTHERMAL CALORIMETRY

General Motors (GM) recently purchased an iso-BTC after extensive trials with their batteries samples, even though they have adiabatic calorimeters available to them. Here’s why.

Fires and explosions involving Li-ion batteries occur when heat is not removed effectively and leads to a rise in temperature. Thermal management systems are designed to prevent such incidents but can only do so if they are designed to handle the necessary heat load – which raises the question:  how can this load be determined?

The answer is HEL’s iso-BTC, which works exactly like a thermal management system except it reports how much heat is being removed while connected to real battery samples.  Many companies fail to appreciate the difference in data from an isothermal calorimeter and the more commonly used adiabatic type (such as HEL’s BTC-500 based on the “ARC” principle).

Typical results are plotted below where the heat load (power loss) is shown at three different discharge rates, for the same battery at the same (constant) temperature. The test can be repeated at different temperatures (for example between -40 to + 100C) to determine the effect of weather conditions

We have prepared a FREE application note, which highlights key performance indicators of thermal control data based on isothermal calorimetry, which can be found here or copy and paste the link below in your browser http://helgroup.com/marketing/isothermal

We have prepared a FREE application note, which highlights key performance indicators of thermal control data based on isothermal calorimetry, which can be found here or copy and paste the link below in your browser http://helgroup.com/marketing/isothermal

See Our Webinar: Faster and Better Process Development Using Parallel Reactor Platforms and DoE

This webinar focuses on the use of multiple (parallel) reactor platforms, which is becoming an established practice in pharma and other sectors as well as the use of DoE to direct the experimental effort and analyze the data. The webinar also highlights the results of many different process development studies to illustrate the range of parallel reaction instruments available.
Examples from synthetic organic chemistry in general, as well as heterogeneous catalysis (including hydrogenation in flow reactors) and crystallization studies, are used to describe the benefits of these techniques.

To Download PDF Of This Webinar, please click on this link

Register NOW For Free DoE Webinar- June 8th 2016, 3.00PM (BST)

DoE WebinarFaster and Better Process Development Using Parallel Reactor Platforms and DoE.

Competitive pressures within the chemical process industry require that more processes be developed quickly and with better results.
The use of multiple (parallel) reactor platforms is becoming an established practice in pharma and other sectors as well as the use of DoE to direct the experimental effort and analyze the data. This webinar will present the results of many different process development studies to illustrate the range of parallel reaction instruments available.
Examples from synthetic organic chemistry in general, as well as heterogeneous catalysis (including hydrogenation in flow reactors) and crystallization studies, will be used to describe the benefits of these techniques.

Click Here To Register NOW & For More Details