BioXplorer 400
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BioXplorer 400


The BioXplorer 400 provides the ideal platform for bioprocess development and optimisation using 4 or 8 reactors in parallel with fermentation working
volumes from 20ml to 150 ml // 50 to 400 ml.
This volume range provides high quality data for reliable prediction of large scale performance over a wide range of conditions.
The system is highly flexible allows interchangeable use of smaller vessels with working volumes of just 20ml. The smaller vessels are highly suitable for data rich screening campaigns.
The modular design and extensive list of options means the BioXplorer 400 can be adapted to any application including microbial fermentation, C1 Gas fermentation and mammalian cell culture.

| Most versatile bioprocessing platform for bioprocess development and optimisation
| High information content and excellent scalability to large scale bioreactors
| Reduce media costs and optimise the use of bench space
| Optional elevated pressure design to 10 bar

| Parallel processing of 4 to 8 independent reactors with any size of bioreactor to 500ml
| Individual temperature and agitation control
| Proprietary mechanical drive or optional overhead drive stirring
| Integrated individual liquid and gas feeds with options for gas mixing.
| Control of all parameters including pH, DO, and options for OD, foam detection and level.
| Optional Integrated exhaust gas analysis (OUR/CER)

| Reusable glass or stainless steel reactors for standard or elevated pressure fermentations.
| Standard or customised head plates to accommodate all probes and resources used at larger scale
| Working volumes from 50 ml to 400 ml thereby significantly reducing reagent costs, but allowing continued sampling and downstream processing
| 20ml to 150ml reactors can also be used interchangeable

| Multi-reactor control software with unlimited step recipe planning. Plans can be changed online at any time without process interruption
| Start and stop reactors individually or simultaneously
| Manage which parameters are logged and recorded with
customisable tabular and graphical displays
| Export data functions and integration with in-house electronic lab notebooks and record keeping systems
| DoE and QbD package integration

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