HEL has developed the concept of "suspended" magnetic stirrers where common mechanical stirrer designs (such as pitched turbine) can be used with magnetic stirrer-motors instead of overhead motors. The company has addressed the inherent difficulties of multi-reactor stirring on such a small footprint, with powerful motors and magnets and adaptive software control. The suspended stirring delivers good mixing to most applications - even slurries - and is particularly suited to the powerful motors of the PB4. The more demanding applications present greater challenges to the smaller motors of the PB8, but recent improvements have enhanced the application range and performance.

This new simple system gives users greater control and flexibility - it is ideal when small vial with magnetic fleas are used, but can be used with any magnetic stirrer.

Fully automated speed-control is still available with the added ability to detect if the stirrer becomes decoupled from the drive magnets and with adaptive controls which automatically reduce setpoints if the stirrer is decoupling at the set speed. For common solvents and even slurries, this provides excellent mixing that is reliable and yet simple and inexpensive.

Contact marketing@helgroup.com for further details

Click here to watch a short video about the PolyBLOCK

Alongside HEL's Managing Director, Dr Jasbir Singh who will be running the morning Safe Scale Up Workshop, speakers include scientists from Dr Reddy's Lab, Intertek and Pfizer that will share their experiences and discuss various aspects of calorimetry and process safety.

Download Agenda

For further information and to register contact marketing@helgroup.com, +44 (0)20 8736 0640 or call Dinesh Malviya at HEL India office on +91-22-22927171/25975110.

The day will be aimed at both new and existing users, and will be split between workshop and training &ndash tailored to the delegates interests &ndash and selected  lectures by HEL users and other experts in the safety field.

Further details and registration information available in the UK from Hadas Mills, Marketing Manager (+44 20 8736 0640) marketing@helgroup.com, or in India from Dinesh Malviya, Country Manager (+91-22-22927171/25975110) dmalviya@helindia.com.

For further information contact HEL Inc, info@hel-inc.com, or call + 609-912-1551

The SAS analyzer is a modernized and improved version of the Fisher Model 95 Sub-Sieve Sizer. Capitalizing on HEL's extensive knowledge and experience in laboratory automation, the SAS has drastically improved the well-established air-permeability particle sizing technique. The instrument combines the benefits of true unattended operation, ease of use, touch-screen control, and data capture using HEL's proprietary WinISO software platform, an innovative development which sets a worldwide standard for instrument operation and system integration.

Air-permeability techniques generate average specific surface area data for powder samples. The specific surface area of particles has a significant impact on the physical properties of powders and has been the focus of much attention from pharmaceutical, paint, toner, and geological industries. The SAS has particular applicability to pharmaceutical quality control where quick and reproducible SAS specific surface area analyses can be used to control batch-to-batch variation in important properties such as bioavailability and drug delivery.

HEL's Managing Director, Dr Jasbir Singh commented  " The Subsieve Autosizer fits well within Particulate Systems product portfolio. We developed it in collaboration with AstraZeneca and we believe that our collaboration with Micromeritics and Particulate Systems to distribute it globally will allow the product to reach the relevant customer base more effectively. &ldquo

More information on the Subsieve Autosizer

The Subsieve Autosizer on Particulate Systems website

Designed for use by early stage synthetic chemists with just a few mouse clicks, existing workflows can be enriched with the early generation of process safety information. The system delivers information about end-of-reaction, changes in mechanism, influence on rate of temperature and other relevant variables as well as thermal hazard.

Crucially, no specialist user knowledge is required the only input is a calibration parameter which can be selected from a built-in library. Simple tools for extending the library, (again requiring no user knowledge) are included in the package. Implementation on HEL's single and multiple reactor platforms is possible as well as on existing jacketed vessels.

More about On-line Calorimetry

The platform permits either 4 or 8 different studies to be simultaneously monitored over a range of concentrations using working volumes from around 1ml upward - even 500ml vessels can be used.

Barret at UCL Dublin(1) used a solvent/anti-solvent combination on a commercial API to enhance quality by design (QbD).

In the new system, converting the recorded data to a classic MSZW plot can now be done live after each step or at the end of the experiment. Previously, the information had to be taken off line for analysis. Existing CrystalSCAN units can also be upgraded with this new feature.

1 Reference Barret at UCL Dublin, read the Application Note