See Our Webinar: Faster and Better Process Development Using Parallel Reactor Platforms and DoE

This webinar focuses on the use of multiple (parallel) reactor platforms, which is becoming an established practice in pharma and other sectors as well as the use of DoE to direct the experimental effort and analyze the data. The webinar also highlights the results of many different process development studies to illustrate the range of parallel reaction instruments available. Examples from synthetic organic chemistry in general, as well as heterogeneous catalysis (including hydrogenation in flow reactors) and crystallization studies, are used to describe the benefits of these techniques. To Download PDF Of This Webinar, please click on this link

Research Scale Pressure Reactors

The need for “tool-less” leak tight seals Demanding chemistries often require more extreme process conditions which need pressure reactors. A key to doing chemistry under pressure is to use reactors that are simple to use while at the same time being safe – covering single and parallel operation and a over a range of volumes. At the small volume end, HEL has developed “Research Scale” Pressure Reactors where a range of volumes can fit a single heat plate: Mini: Common head plate to fit 16,25 and 50 ml – magnetically stirred Midi: Common head plate to fit 75, 150, 300 and 500 ml – magnetically or overhead stirred. These reactors,… Continue Reading

Hybrid Reactor Solutions For Bioreactors And Catalytic Synthetic Chemistry

HEL ChemSCAN For Catalyst, Bio & Chemical Applications HEL offer reactors used for  “green” fuels (bio-diesel, bio-ethanol etc.), as well as bioreactors for cell and bacterial applications. These bio applications have a lot in common with high-pressure solutions for synthetic chemical screening and hydrogenation processes. The switch to 2nd and 3rd  generation bio-fuels (using biomass sources such as food-waste, stalks from crop, etc.) requires more extreme temperatures and pressures, not unlike heterogeneous catalytic processes. HEL’s unique position as both a bio and synthetic chemistry supplier is allowing the growing number of cross-over applications to be readily satisfied. Download our full brochure at http://bit.ly/HELhighpressure

New Bioreactor Solutions, Provides 5 Times The Productivity Of Conventional Reactors

FREE WHITE PAPER DOWNLOAD Robotic culture platform with HEL minibioreactors Parallel platforms can also be integrated with bioreactors – hence 4 or 8 reactor parallel stations are now possible with a compact footprint that includes all the features of high specification applications – pH, DO, agitation, liquid dosing, independent temperature control. A recent project extended this concept still further with a set of 24 independent reactors for TWB in France, involving the integration of a Hamilton robot and HEL bioreactor system. The final design – a “culture robot” – allows, among other things, identification of optimal culture conditions or generation of successfulstrains, in less than a fifth of the time… Continue Reading

DoE using Parallel Automated Reactor Systems- FREE White Paper

Statistical Design of Experiments (DoE) is widely recognized as the most effective approach for process development. Application of this technique can take a long time – weeks or even months – unless the right experimental tools are available so that quality results can be obtained at speed. The best tools consist of multiple reactors that can work in parallel as well as independently with accurate control and logging of all key parameters. HEL has a range of parallel chemistry platforms (4 and 8 reactor set ups as standard) which include applications such as: -Heterogeneous catalysis under pressure (e.g for hydrogenations) – HP ChemScan -General synthetic chemistry at wide temperature ranges… Continue Reading