Rapidly Evaluate Catalysts & Optimize Reaction Conditions

With the HEL CAT 7, CAT 18, CAT 24, PluCAT, DigiCAT products for Rapidly Evaluate Catalysts & Optimize Reaction Conditions

One challenge faced by researchers in catalyst development is the need to quickly evaluate different catalysts and optimise reaction conditions. However, accessing affordable, high pressure, high temperature screening devices is equally challenging. The HEL CAT blocks: |Provide an affordable, entry level range of catalyst research tools. |Are available in 7, 18 or 24 vial configurations the CAT blocks allow primary catalyst screening and basic process optimisation at relatively low cost. |Can be used with conventional hotplate stirrers and all gas and pressure fittings are preinstalled. |Are widely used successfully at many Universities both as research and teaching tools. |Allows to undertake rapid parallel catalysis and thereby facilitate quicker downstream analysis.… Continue Reading

See Our Webinar: Faster and Better Process Development Using Parallel Reactor Platforms and DoE

This webinar focuses on the use of multiple (parallel) reactor platforms, which is becoming an established practice in pharma and other sectors as well as the use of DoE to direct the experimental effort and analyze the data. The webinar also highlights the results of many different process development studies to illustrate the range of parallel reaction instruments available. Examples from synthetic organic chemistry in general, as well as heterogeneous catalysis (including hydrogenation in flow reactors) and crystallization studies, are used to describe the benefits of these techniques. To Download PDF Of This Webinar, please click on this link

The Next Step In Flow Chemistry Under Pressure : The FlowCAT SA

Contrary to popular belief, “Flow Chemistry” has extensively been used in small scale chemical production for decades, especially for chemistry under pressure. The HEL FlowCAT is a bench-top platform enabling continuous flow heterogeneous catalysis for use in applications including hydrogenation, carbonylation, oxidation and is widely used in the pharmaceutical and fine chemical industries. In response to customer requests, a lower price platform is now being launched – The FlowCAT SA. The FlowCAT SA provides a more focused set of working conditions, and the control is semi-automated (hence “SA”). The compact mechanical design is of the same quality and robustness (of the original FlowCAT), but working pressure and the temperature are… Continue Reading

Research Scale Pressure Reactors

The need for “tool-less” leak tight seals Demanding chemistries often require more extreme process conditions which need pressure reactors. A key to doing chemistry under pressure is to use reactors that are simple to use while at the same time being safe – covering single and parallel operation and a over a range of volumes. At the small volume end, HEL has developed “Research Scale” Pressure Reactors where a range of volumes can fit a single heat plate: Mini: Common head plate to fit 16,25 and 50 ml – magnetically stirred Midi: Common head plate to fit 75, 150, 300 and 500 ml – magnetically or overhead stirred. These reactors,… Continue Reading

DoE using Parallel Automated Reactor Systems- FREE White Paper

Statistical Design of Experiments (DoE) is widely recognized as the most effective approach for process development. Application of this technique can take a long time – weeks or even months – unless the right experimental tools are available so that quality results can be obtained at speed. The best tools consist of multiple reactors that can work in parallel as well as independently with accurate control and logging of all key parameters. HEL has a range of parallel chemistry platforms (4 and 8 reactor set ups as standard) which include applications such as: -Heterogeneous catalysis under pressure (e.g for hydrogenations) – HP ChemScan -General synthetic chemistry at wide temperature ranges… Continue Reading