“NEW” Tandem Gas Analyser Data Capture Software

The new Tandem gas analyser data capture software allows the convenient monitoring and visualisation of exhaust gas data from all Tandem Gas Analysers   Advantages of the Tandem data capture software: | Real-time monitoring of %CO2 and %O2 from the off-gas of any bioreactor | Export data in CSV format | Available as a stand-alone portable unit | Works with any Tandem gas analyser | Run up to 18 parallel processes | Simple to use | Automatically calculates CER, OUR & RQ with HEL BioXplorer systems The Tandem Family of Gas Analysers offers you sophisticated CO2 and O2 gas measurement at a similar price to your other standard probes and… Continue Reading

New HEL BioXplorer 100 & 400 Mini-Bioreactor System

The Mini-Bioreactor System For Rapid Parallel Bioprocessing

Introducing The BioXplorer 100 & BioXplorer 400 Mini-Bioreactor System The feature rich, modular design with an extensive list of options means the BioXplorer 100 and 400 can be adapted to any application including microbial fermentation, C1 Gas fermentation and mammalian cell culture. These mini-bioreactors provide the ideal platform for bioprocess development and optimisation using 4 or 8 reactors in parallel with fermentation working volumes from 20 ml to 400 ml (depending on c.onfiguration) The BioXplorer 100 The BioXplorer 100 is a high throughput, bioprocess screening system designed for fermentation working volumes of just 20ml to 150ml in blocks of 8 individually controlled bioreactors. Blocks can be combined to give even… Continue Reading

The NEW Bioreactor Inventory Control (BIC)

The control of culture volumes in bioreactors is critical to ensure optimum conditions for cell growth and to achieve high cell densities. HEL has developed a system that is based on proven technology but is more traditionally used with large scale fermenters. The Bioreactor Inventory Control (BIC) constantly measures ONLY the volume of the bioreactor contents. The BIC is also immune to effects of foaming that can hinder accurate level detection. The BIC technology can be easily added to any reactor, either to the head plate or remote from the bioreactor, and is the size of a matchbox. The system can accurately maintain the volume of any bioreactor regardless of… Continue Reading

NOW SHOWING Our Webinar Innovations In Miniature Bioreactor Technology

The webinar shows HEL innovative screening technology developed for Gas fermentation: Miniature bioreactors from 20 ml to 500 ml that can be operated in parallel at pressures to 10 bar. Proven scalability based on classical bioreactor design and geometry Advanced gas management methods Full automation from inoculation to sampling and downstream processing How to configure a system for C1 gas process development   To download pdf of this webinar, click here

HEL at RAFT 2015

HEL are exhibiting at RAFT (Recent Advances in Fermentation Technology), an annual SIMB event. November 8- 11, 2015 Location: Hilton Clearwater Beach Hotel, Clearwater Beach, FL We will be showing our latest innovations in bioreactor solutions which offers the most compact parallel screening systems available with working volumes from 20 ml to 2. 5 L and with pressure capabilties up to 5 bar

The BioVIS – Total Cell Density & Biomass Monitoring In Any Bioreactor

The BioVIS from Magellan BioTech (a HEL group company) offers the following unique features: Ease Of Operation BioVIS allows the online monitoring of total cell growth and biomass using optical density technology, which can reduce or replace the need for online sampling. Simply insert the sterilisable probe inside the bioreactor and track growth. Compatible With All Major Brands Of Bioreactors This is a compact, portable and easy to use unit which is compatible with all major brands of bioreactor, including: – Sartorius Stedim – Applikon – Pierre Guerin – Finesse – Infors – New Brunswick And many more ……… Features Monitor and log total cell density in any fermenter Plug… Continue Reading

Hybrid Reactor Solutions For Bioreactors And Catalytic Synthetic Chemistry

HEL ChemSCAN For Catalyst, Bio & Chemical Applications HEL offer reactors used for  “green” fuels (bio-diesel, bio-ethanol etc.), as well as bioreactors for cell and bacterial applications. These bio applications have a lot in common with high-pressure solutions for synthetic chemical screening and hydrogenation processes. The switch to 2nd and 3rd  generation bio-fuels (using biomass sources such as food-waste, stalks from crop, etc.) requires more extreme temperatures and pressures, not unlike heterogeneous catalytic processes. HEL’s unique position as both a bio and synthetic chemistry supplier is allowing the growing number of cross-over applications to be readily satisfied. Download our full brochure at http://bit.ly/HELhighpressure

New Bioreactor Solutions, Provides 5 Times The Productivity Of Conventional Reactors

FREE WHITE PAPER DOWNLOAD Robotic culture platform with HEL minibioreactors Parallel platforms can also be integrated with bioreactors – hence 4 or 8 reactor parallel stations are now possible with a compact footprint that includes all the features of high specification applications – pH, DO, agitation, liquid dosing, independent temperature control. A recent project extended this concept still further with a set of 24 independent reactors for TWB in France, involving the integration of a Hamilton robot and HEL bioreactor system. The final design – a “culture robot” – allows, among other things, identification of optimal culture conditions or generation of successfulstrains, in less than a fifth of the time… Continue Reading

Scalability Study With The HEL Xplorer Bioprocessing Platform

HEL Bioreators

The scalability study was based on matching kLa values in both a 100 ml miniature bioreactor and a 2L bioreactor. The table below illustrates how closely the biomass concentration and DOT profiles compare at the two scales, with µmax values that differ by only 0.03 h-1. A greater final biomass concentration, 5.5 g.L-1, was produced in the 2 L bioreactor as a significantly larger initial inoculum, 6.7%, was used. The trends for oxygen depletion during the linear growth phase as well as time taken for both systems to become oxygen limited are similar and reproducible in both cases. This data quality at approximately 100 ml scale combined with the miniature… Continue Reading